Hexane → HCID 178506815, compound

HRID 990295Notes

Reaction equation

HRID 990295 reaction equation
[CH2:1]([Li:5])[CH2:2][CH2:3][CH3:4].[CH3:6][CH2:7][CH2:8][CH2:9][CH2:10]C>C(OCC)C>[CH:1]1([Li:5])[C:10]2[C:4](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:3]=[CH:2]1

Participants

4

Reactant 2

HCID 8058HexaneHCID 178418339Butyllithium

Product 1

HCID 178506815HCID 178506815, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

18.8 ml (30.0 mmol) of a 1.60 molar solution of n-butyllithium in n-hexane are added dropwise at room temperature to a solution of 30.0 mmol of the appropriately substituted indene in 150 ml of diethyl ether. The mixture is stirred at this temperature for two hours. The solvent is removed in an oil pump vacuum and the residue is suspended overnight in 100 ml of pentane. The suspension is filtered through a frit and the residue is washed with a little pentane. The product is dried in an oil pump vacuum.

Workup

  1. customThe solvent is removed in an oil pump vacuum
  2. waitthe residue is suspended overnight in 100 ml of pentane
  3. filtrationThe suspension is filtered through a frit
  4. washthe residue is washed with a little pentane
  5. customThe product is dried in an oil pump vacuum

Sources & evidence

ORD record
ord-8ef2968fd5ac45ffbe55e835f7a4c577
Source dataset
uspto-grants-2002_10
Patent number
US06458982B1

Reaction notes

Loading…