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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 990585Generated: October 26, 2026

Diethylene Glycol Monoethyl Ether → Amitriptyline

https://huagongshe.com/reaction/990585

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylene Glycol Monoethyl EtherHCID 8146—
ReactantAmitriptyline HydrochlorideHCID 11065—
ProductAmitriptylineHCID 2160—

Reaction Steps

0.750 gm amitriptyline hydrochloride USP, is wetted with 1.5 ml of ethoxy diglycol reagent, and stirred into 75 gm of the base cream prepared as per example 3 and triple milled. A cream-type preparation results which contains amitriptyline hydrochloride @ 10 mg/ml

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06461600B1
Source datasetuspto-grants-2002_10
ORD IDord-7b0db97616db43d3a0ee7da715f224af
Source noteuspto-grants-2002_10