Hydrochloric Acid → HCID 70144474, compound

Participants

Reaction Steps

In a 300 ml three neck distillation flask, the compound prepared above in (6b) (20.4 g, 77.2 mmol) and methanol (50 ml) were placed. To the flask, aqueous solution (30 ml) of potassium hydroxide (8.66 g, 154 mmol) was dropwise added. After the mixture was refluxed for 2 hours, dilute hydrochloric acid was added to precipitate crystalline product. The product was collected by filtration, and recrystallized from acetonitrile to obtain the titled compounds (16.8 g, yield: 87%).

Provenance & Evidence