5-Chloro-2-methoxy-4-nitrobenzoic acid → N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-chloro-2-methoxy-4-nitrobenzamide

HRID 99076Notes

Reaction equation

HRID 99076 reaction equation
[Cl:13][c:14]1[c:15]([N+:25](=[O:26])[O-:27])[cH:16][c:17]([O:23][CH3:24])[c:18]([C:19](=[O:20])[OH:21])[cH:22]1.[NH2:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[CH2:7][N:6]([CH3:12])[CH2:5][CH2:4]2>>[NH:1]([c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[CH2:7][N:6]([CH3:12])[CH2:5][CH2:4]2)[C:19]([c:18]1[c:17]([O:23][CH3:24])[cH:16][c:15]([N+:25](=[O:26])[O-:27])[c:14]([Cl:13])[cH:22]1)=[O:20]

Participants

3

Reactant 2

HCID 137856695-Chloro-2-methoxy-4-nitrobenzoic acidHCID 141712692-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine

Product 1

HCID 18687433N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-chloro-2-methoxy-4-nitrobenzamide

Sources & evidence

ORD record
ord-07b3198daa1943f590e5c9574c3520fc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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