反应详情

To a solution of 1-(4-Fluoro-phenyl)-2-methyl-propan-1-ol (1.6 g) in acetone (10 mL) at 0° C. is added Jones reagent (20 mL) with stirring. After 10 minutes excess Jones reagent is destroyed by addition of isopropyl alcohol. Diethyl ether is added followed by anhydrous magnesium and the mixture is filtered and evaporated to give the product, a yellow oil (1.2 g).

1. customAfter 10 minutes excess Jones reagent is destroyed by addition of isopropyl alcohol
2. additionDiethyl ether is added
3. filtrationthe mixture is filtered
4. customevaporated
5. customto give the product