HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 136062352, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Benzoic acid, 2-mercapto-, methyl ester | HCID 21009 | — |
| Reactant | 4-(Bromoacetyl)benzonitrile | HCID 98654 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 136062352 | HCID 136062352 | — |
Reaction Steps
A mixture of 4-cyanophenacyl bromide (3.0 g), methyl thiosalicylate (2.25 g), sodium methoxide (1.52 g) and ethanol (100 ml) was boiled under reflux for 3.5 hours. The mixture was cooled and diluted with 2M hydrochloric acid (100 ml). A precipitate was collected by filtration and recrystallized from ethanol to give 2-(4-cyanobenzoyl)-3-hydroxybenzo[b]thiophene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06462036B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-044cd68a96864c66960bec72c066491c |
| Source note | uspto-grants-2002_10 |