Benzoic acid, 2-mercapto-, methyl ester → HCID 135997745, compound

Participants

Reaction Steps

In a similar manner to Example 58, a mixture of methyl thiosalicylate (2.76 g), 4-nitrophenacyl bromide (4.0 g), sodium methoxide (1.94 g) and ethanol (200 ml) gave 2-(4-nitrobenzoyl)-3-hydroxybenzo[b]thiophene of which 2.25 g was reacted with hydrazine hydrate (6 ml) in a similar manner to Example 58, to give 3-(4-aminophenyl)-1H-[1]benzothieno[3,2-c]pyrazole, m.p. 113-115° C.

Provenance & Evidence