Hydrochloric Acid → HCID 9860034, compound

Participants

Reaction Conditions

Reaction Steps

3-Phenylindeno[1,2-c]pyrazol-4-(1H)-one (2.4 g) was suspended in toluene (40 ml) under nitrogen and trimethyl aluminium (2.2 ml of a 2M solution in heptane) was added at 20° C. with stirring. The mixture was heated at 90° C. for 16 hours, then cooled to ambient temperature and poured on to crushed ice (approx. 600 ml) containing concentrated hydrochloric acid (30 ml). The precipitated solid was collected by filtration and recrystallized from ethyl acetate with hot filtering to give 4-methyl-3-phenyl-1,4-dihydroindeno[1,2-c]pyrazol-4-ol, m.p.154-155° C.

Provenance & Evidence