Sodium Hydroxide → HCID 11012350, compound

HRID 991054Notes

Reaction equation

HRID 991054 reaction equation
C([O:3][C:4](=[O:22])[C:5]([CH3:21])([S:13]([C:16]1[S:17][CH:18]=[CH:19][CH:20]=1)(=[O:15])=[O:14])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)C.[OH-].[Na+]>C(O)C>[CH3:21][C:5]([S:13]([C:16]1[S:17][CH:18]=[CH:19][CH:20]=1)(=[O:15])=[O:14])([CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:4]([OH:22])=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 11782728HCID 11782728, compound

Product 1

HCID 11012350HCID 11012350, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Methyl-3-phenyl-2-(thiophene-2-sulfonyl)-propionic acid was prepared according to the general method as outlined in example 9. Starting from 2-methyl-3-phenyl-2-(thiophen-2-sulfonyl)-propionic acid ethyl ester (5.0 g, 15 mmol), ethanol (30 mL) and 10 N sodium hydroxide (10 mL). Yield 5.6 g MS 310.0 (M+H).

Sources & evidence

ORD record
ord-d6b3f3a5acef430d945f36c9e79ce9f9
Source dataset
uspto-grants-2002_10
Patent number
US06462073B2

Reaction notes

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