HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11048407, compound → HCID 11015085, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11048407 | HCID 11048407 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 11015085 | HCID 11015085 | — |
Reaction Steps
1-Cyclooctyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid was prepared starting from 1-cyclooctyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester (8 g, 183 mmol) dissolved in methanol (200 ml) and 10N NaOH (25 ml). The resulting reaction mixture was worked up as outlined in example 83. Yield 2.36 g (32%); white powder; mp 180° C.; MS: 410 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06462073B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-f75a677996d44e67b68c1bf67ffdfe25 |
| Source note | uspto-grants-2002_10 |