HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11070555, compound → HCID 10972070, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11070555 | HCID 11070555 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Solvent | MeOH tetrahydrofuran | HCID 21899815 | — |
| Product | HCID 10972070 | HCID 10972070 | — |
Reaction Steps
1-Benzyl-4-(4butoxy-benzenesulfonyl)-piperidine-4-carboxylic acid was prepared starting from 1-benzyl-4-(4butoxy-benzenesulfonyl)-piperidine-4-carboxylic acid ethyl ester (5.1 g, 11.1 mmol) dissolved in THF:methanol 3:1 and 10N NaOH (10 ml). The resulting reaction mixture was worked up as outlined in example 83. Yield 2.66 g (56%); off white solid; mp 210° C.; MS: 432 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06462073B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-1b1204f5084249e2b098bf2017b27322 |
| Source note | uspto-grants-2002_10 |