3,4-Dichloro-N,N-bis(2-chloroethyl)benzenemethanamine → HCID 11005920, compound

Participants

Reaction Steps

4-(4-Butoxy-benzenesulfonyl)-1-(3,4-dichloro-benzyl)-piperdine-4-carboxylic acid ethyl ester was prepared according to the general method outlined in example 83. Starting from (4-butoxy-benzenesulfonyl)acetic acid ethyl ester (13.2 g 44 mmol) (3,4-dichloro-benzyl)-bis-(2-chloro-ethyl)-amine (14.3 g, mmol). Yield 14.1 g (60%), white solid, MP 86° C.; MS: 527.9 (M+H)+

Provenance & Evidence