Cyclopropanemethanol → Diphenylacetyl-carbamic acid cyclopropylmethyl ester

HRID 991197Notes

Reaction equation

[C:1]1([CH:7]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:8]([N:10]=[C:11]=[O:12])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:19]1([CH2:22][OH:23])[CH2:21][CH2:20]1>>[CH:19]1([CH2:22][O:23][C:11](=[O:12])[NH:10][C:8](=[O:9])[CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH2:21][CH2:20]1

Participants

Reactant 2

HCID 75644Cyclopropanemethanol

HCID 11264874Diphenylacetyl isocyanate

Product 1

HCID 11781834Diphenylacetyl-carbamic acid cyclopropylmethyl ester

Procedure

The title compound, white solid, m.p.=108° C., MS: m/e=309.4 (M+H+) was prepared in accordance with the general method of example 1 from diphenylacetyl isocyanate and cyclopropyl-methanol.

Sources & evidence

ORD record: ord-b485c77657b045f9a7c5a482ab4d2e81
Source dataset: uspto-grants-2002_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06462198B1

Reaction notes

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