9H-xanthene-9-carbonyl chloride → 9H-Xanthene-9-carboxylic acid (5-ethyl-oxazol-2-yl)-amide

HRID 991240Notes

Reaction equation

HRID 991240 reaction equation
[CH2:1]([C:3]1[O:7][C:6]([NH2:8])=[N:5][CH:4]=1)[CH3:2].[CH:9]1[C:22]2[CH:21]([C:23](Cl)=[O:24])[C:20]3[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=3)[O:14][C:13]=2[CH:12]=[CH:11][CH:10]=1>>[CH2:1]([C:3]1[O:7][C:6]([NH:8][C:23]([CH:21]2[C:22]3[CH:9]=[CH:10][CH:11]=[CH:12][C:13]=3[O:14][C:15]3[C:20]2=[CH:19][CH:18]=[CH:17][CH:16]=3)=[O:24])=[N:5][CH:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 27608929H-xanthene-9-carbonyl chlorideHCID 226610805-Ethyl-2-oxazolamine

Product 1

HCID 538935599H-Xanthene-9-carboxylic acid (5-ethyl-oxazol-2-yl)-amide

Procedure

The title compound, white solid, m.p. 212-213° C. and MS: m/e=320.1 (M+) was prepared in accordance with the general method of example 44a from 5-ethyl-oxazol-2-ylamine [Ber. 95, 2419(1962)] and 9-xanthene-carboxylic acid chloride.

Sources & evidence

ORD record
ord-974084ae67024601a55b1ded993edd81
Source dataset
uspto-grants-2002_10
Patent number
US06462198B1

Reaction notes

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