Water → Cyclooctanone

Participants

Reaction Steps

10.6 g of stabilized IBX prepared as in Example 10 are suspended in 60 ml of N-methylpyrrolidone at 20° C., and 2 g of cyclooctanol are added dropwise while maintaining the temperature at from 20° C. to 25° C. After 2 hours, agitation, the medium is poured into a mixture of 130 ml of water and 80 ml of toluene; the pH of the aqueous phase is brought to approximately 7 by the addition of aqueous NaOH and the organic phase, after separation of the insoluble material formed and of the aqueous phase, is concentrated to give 1.4 g of pure cyclooctanone (NMR and GPC)

Provenance & Evidence