Triphenylphosphine → HCID 70161140, compound

Participants

Reaction Steps

A fully reacted mixture of equimolar amounts of diethyl azodicarboxylate and triphenylphosphine in THF is admixed with equimolar amounts of 4-(5-undecyl-pyrimidin-2-yl)phenol and 5-propyl-tetrahydrothiophen-2-yl-methanol (prepared by LiAIH4 reduction of methyl 5-propyl-tetrahydrothiophene-2-carboxylate). The mixture is stirred for 24 h at room temperature and then evaporated to dryness under reduced pressure. Purification by chromatography (silica gel, dichloromethane) and recrystallization affords the target compound. The compounds (I-13) and (I-14) can be obtained in a similar manner.

Provenance & Evidence