HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,7-Dibenzyl-3,7-diazabicyclo[3.3.1]nonane → 3-Benzyl-3,7-diazabicyclo[3.3.1]nonane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,7-Dibenzyl-3,7-diazabicyclo[3.3.1]nonane | HCID 47341 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Benzyl-3,7-diazabicyclo[3.3.1]nonane | HCID 13059482 | — |
Reaction Steps
A solution of 3,7-dibenzyl-3,7-diazabicyclo[3.3.1]nonane (from step (ii) above; 97 g; 6.4 mmol) in aqueous ethanol (95%) was hydrogenated over 5% Pd/C at 1 atm. until tic indicated that the reaction was complete. The catalyst was removed by filtration through a pad of Celite®, and the filtrate concentrated under reduced pressure to give the sub-title compound in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465481B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-a66ea2ed9f854dca8d4a11e137a41558 |
| Source note | uspto-grants-2002_10 |