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HRID991488

反应详情

EQUATION

反应方程式

HRID 991488 的结构方程式

REACTANTS

反应物

3
结构：O=C(N=NC(=O)N1CCCCC1)N1CCCCC1
HCID73042

1,1′-(1,2-Diazenediyl)bis[1-(1-piperidinyl)methanone]

C12H20N4O2

结构：C=CCC(O)c1ccc(C#N)cc1
HCID11019345

未命名化合物

结构：Oc1ccc(OC2CCCCO2)cc1
HCID11745519

4-[(Oxan-2-yl)oxy]phenol

C11H14O3

PRODUCTS

生成物

1
结构：C=CCC(Oc1ccc(OC2CCCCO2)cc1)c1ccc(C#N)cc1
HCID22235671

未命名化合物

收率 68.7%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cc1ccccc1
溶剂HCID1140

Toluene

C7H8

CONDITIONS

反应条件

温度
0 °C

PROCEDURE

实验过程

4-(Tetrahydro-2H-pyran-2-yloxy)phenol (19.0 g; 0.1 mol) and 4-(1-hydroxy-3-butenyl)benzonitrile (17.8 g; 0.1 mol) was mixed in toluene, and cooled to 0° C. (under nitrogen). TBP (22.9 g; 0.11 mol) was added, followed by ADDP. The mixture was stirred at rt overnight, filtered, and evaporated. Purification by chromatography on silica gave 24 g (68.7%) of the desired compound.

WORKUP

后处理

  1. additionTBP (22.9 g; 0.11 mol) was added
  2. filtrationfiltered
  3. customevaporated
  4. customPurification by chromatography on silica