Hydrogen Peroxide → HCID 11689554, compound

Participants

Reaction Steps

Prepared from 4-(5-benzo[1,3]dioxol-5-yl-4-pyridin-2-yl-oxazol-2-yl)-benzonitrile using hydrogen peroxide and methanolic potassium carbonate according to Example 16 and isolated in 44% yield. 1H NMR (DMSO) δ: 6.15 (2H, s), 7.08-7.16 (2H, m), 7.45-7.54 (2H, m), 7.95-7.99 (1H, m), 8.02 (1H, br. s), 8.08 (1H, br. s), 8.12-8.15 (2H, m), 8.22 (1H, dd, J=7 and 1 Hz), 8.48 (1H, d, J=8 Hz), 8.74 (1H, d, J=8 Hz); m/z (API) 386 (M+H+).

Provenance & Evidence