Ammonium Acetate → HCID 11632381, compound

Participants

Reaction Steps

4-(3-Benzo[1,3]dioxol-5-yl-4-oxo4-pyridin-2-ylbutanoyl)benzamide (1.69 g; 4.2 mmol) and ammonium acetate (2.1 g; 27.3 mmol) were reacted together according to the method described in Bioorg. Med. Chem. Letters, 1998, 8, 2689-2694. The title compound was isolated as a brown powder from methanol (126 mg; 8%). 1H NMR (DMSO) δ: 6.04 (2H, s), 6.82-6.93 (4H, m), 7.18-7.32 (3H, m), 7.63-7.74 (1H, m), 7.86-7.96 (5H, m), 8.61 (1H, d, J=4 Hz), 11.63 (1H, brs); m/z (LCMS): 383.9 (M+H)+.

Provenance & Evidence