HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → Ethyl alpha-(1-hydroxy-6-methoxy-2-methyl-1-indanyl)propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Ethyl 2-bromopropionate | HCID 79040 | — |
| Reactant | alpha-(5-Methoxy-2-methyl-3-indenyl)propionic acid | HCID 22393256 | — |
| Product | Ethyl alpha-(1-hydroxy-6-methoxy-2-methyl-1-indanyl)propionate | HCID 22393265 | — |
Reaction Steps
The procedure of Example 35, part (A) is followed using ethyl α-bromopropionate in equivalent quantities in place of ethyl bromoacetate used therein. There is obtained ethyl α-(1-hydroxy-6-methoxy-2-methyl-1-indanyl)propionate, which is dehydrated to ethyl α-(5-methoxy-2-methyl-3-indenyl)propionate in the same manner.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465494B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-97b9fb29c8ee4b49a942b487730b4828 |
| Source note | uspto-grants-2002_10 |