3-Aminopyrrolidine → HCID 22036500, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 4, Step 2, starting from 2-chloro-3-[2-(4-chlorophenoxy)ethoxy]pyrazine* (150 mg, 0.53 mmol) and 3-aminopyrrolidine (247 mg, 2.87 mmol) with the exception that a final extraction step between EtOAc and 5% aqueous NaOH was carried out. This gave 123 mg (69%) of the title product. Anal. (C16H19ClN4O2) H, N; C: calcd, 57.40; found, 56.9. *Prepared according to the procedure described in Example 4, Step 1.

Provenance & Evidence