Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Ethyl [3,5bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]acetate | HCID 135914986 | — |
| Product | HCID 135817488 | HCID 135817488 | — |
Reaction Steps
2.0 g of ethyl [3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]acetate (Example 2) are dissolved in15 ml of ethanol and treated with 0.8 ml of 8 M methylamine in ethanol. The mixture is stirred at 60° C. for 3 h and then cooled. The crystals precipitating in the course of this are filtered off and washed with ethanol. After drying, 2-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]-N-methylacetamide remains as colorless crystals m.p. 247-249° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06465504B1 |
|---|
| Source dataset | uspto-grants-2002_10 |
|---|
| ORD ID | ord-192f1c29a97a4363b7143309f1c24943 |
|---|
| Source note | uspto-grants-2002_10 |
|---|
