HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 135914988, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Acetic acid, 2-hydrazinyl-, ethyl ester, hydrochloride (1:1) | HCID 11593468 | — |
| Reactant | HCID 135817451 | HCID 135817451 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 135914988 | HCID 135914988 | — |
Reaction Steps
6.0 g of chloro-2-(5-chloro-2-hydroxyphenyl)benz[e][1,3]oxazin-4-one (Example 16), 3.0 ml of triethylamine and 3.3 g of ethyl hydrazinoacetate hydrochloride are boiled under reflux for 2 h in 60 ml of ethanol. On cooling, the product precipitates in crystalline form. It is filtered off and washed with ethanol. After drying, ethyl [3,5-bis(5-chloro-2-hydroxyphenyl)-[1,2,4]triazol-1-yl]acetate is obtained as colorless crystals of m.p. 195-200° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465504B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-1f0985ca828f4f499aecd0cce11f798e |
| Source note | uspto-grants-2002_10 |