tert-Butyl 2-(3-methoxycarbonyladamant-1-ylcarbonylamino)pent-4-ynoate → 2-(3-Methoxycarbonyladamant-1-ylcarbonylamino)pent-4-ynoic Acid

HRID 991762Notes

Reaction equation

HRID 991762 reaction equation
[CH3:1][O:2][C:3]([C:5]12[CH2:14][CH:9]3[CH2:10][CH:11]([CH2:13][C:7]([C:15]([NH:17][CH:18]([CH2:26][C:27]#[CH:28])[C:19]([O:21]C(C)(C)C)=[O:20])=[O:16])([CH2:8]3)[CH2:6]1)[CH2:12]2)=[O:4]>C(O)=O>[CH3:1][O:2][C:3]([C:5]12[CH2:14][CH:9]3[CH2:10][CH:11]([CH2:13][C:7]([C:15]([NH:17][CH:18]([CH2:26][C:27]#[CH:28])[C:19]([OH:21])=[O:20])=[O:16])([CH2:8]3)[CH2:6]1)[CH2:12]2)=[O:4]

Participants

3

Reactant 1

HCID 21940505tert-Butyl 2-(3-methoxycarbonyladamant-1-ylcarbonylamino)pent-4-ynoate

Product 1

HCID 98840642-(3-Methoxycarbonyladamant-1-ylcarbonylamino)pent-4-ynoic Acid

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

The title compound was prepared by hydrolysis of the compound from Step A using formic acid as described in Example 43, Step D.

Sources & evidence

ORD record
ord-75c8714bea764ce09ac2e9d16728e933
Source dataset
uspto-grants-2002_10
Patent number
US06465513B1

Reaction notes

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