4-Oxo-2,4,6,7-tetrahydropyrano[3,4-C]pyrrole-1-carbaldehyde → 2-Oxo-3-(4-oxo-2,4,6,7-tetrahydro-pyrano[3,4-c]pyrrol-1-ylmethylene)-2,3-dihydro-1H-indole-5-sulfonic acid isopropylamide

HRID 991804Notes

Reaction equation

HRID 991804 reaction equation
[CH:1]([NH:4][S:5]([C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12](=[O:17])[CH2:11]2)(=[O:7])=[O:6])([CH3:3])[CH3:2].[O:18]=[C:19]1[C:24]2=[CH:25][NH:26][C:27]([CH:28]=O)=[C:23]2[CH2:22][CH2:21][O:20]1>>[CH:1]([NH:4][S:5]([C:8]1[CH:9]=[C:10]2[C:14](=[CH:15][CH:16]=1)[NH:13][C:12](=[O:17])[C:11]2=[CH:28][C:27]1[NH:26][CH:25]=[C:24]2[C:19](=[O:18])[O:20][CH2:21][CH2:22][C:23]=12)(=[O:7])=[O:6])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 98340494-Oxo-2,4,6,7-tetrahydropyrano[3,4-C]pyrrole-1-carbaldehydeHCID 219156105-Isopropylaminosulfonyl-2-oxindole

Product 1

HCID 697073202-Oxo-3-(4-oxo-2,4,6,7-tetrahydro-pyrano[3,4-c]pyrrol-1-ylmethylene)-2,3-dihydro-1H-indole-5-sulfonic acid isopropylamide

Procedure

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid isopropylamide was condensed with 4-oxo-2,4,6,7-tetrahydro-pyrano[3,4-c]pyrrole-1-carbaldehyde to give the title compound.

Sources & evidence

ORD record
ord-320b851666f4454bbb030ec9f53dfa18
Source dataset
uspto-grants-2002_10
Patent number
US06465507B2

Reaction notes

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