4-Oxo-2,4,6,7-tetrahydropyrano[3,4-C]pyrrole-1-carbaldehyde → 1-[6-(2-Methoxy-phenyl)-2-oxo-1,2-dihydro-indol-3-ylidenemethyl]-6,7-dihydro-2H-pyrano[3,4-c]pyrrol-4-one

HRID 991813Notes

Reaction equation

HRID 991813 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:17]=[C:16]2[C:12]([CH2:13][C:14](=[O:18])[NH:15]2)=[CH:11][CH:10]=1.[O:19]=[C:20]1[C:25]2=[CH:26][NH:27][C:28]([CH:29]=O)=[C:24]2[CH2:23][CH2:22][O:21]1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:17]=[C:16]2[C:12]([C:13](=[CH:29][C:28]3[NH:27][CH:26]=[C:25]4[C:20](=[O:19])[O:21][CH2:22][CH2:23][C:24]=34)[C:14](=[O:18])[NH:15]2)=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 98340494-Oxo-2,4,6,7-tetrahydropyrano[3,4-C]pyrrole-1-carbaldehydeHCID 105619756-(2-Methoxyphenyl)-1,3-dihydroindol-2-one

Product 1

HCID 697080841-[6-(2-Methoxy-phenyl)-2-oxo-1,2-dihydro-indol-3-ylidenemethyl]-6,7-dihydro-2H-pyrano[3,4-c]pyrrol-4-one

Procedure

6-(2-Methoxy-phenyl)-1,3-dihydro-indol-2-one was condensed with 4-oxo-2,4,6,7-tetrahydro-pyrano[3,4-c]pyrrole-1-carbaldehyde to give the title compound.

Sources & evidence

ORD record
ord-65e7bac6b43d429b91acde9de7b1bb54
Source dataset
uspto-grants-2002_10
Patent number
US06465507B2

Reaction notes

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