4-Oxo-2,4,6,7-tetrahydropyrano[3,4-C]pyrrole-1-carbaldehyde → 3-[2-Oxo-3-(4-oxo-2,4,6,7-tetrahydro-pyrano[3,4-c]pyrrol-1-ylmethylene)-2,3-dihydro-1H-indol-5-yl]-benzoic acid

HRID 991826Notes

Reaction equation

HRID 991826 reaction equation
[O:1]=[C:2]1[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:11]3[CH:12]=[C:13]([CH:17]=[CH:18][CH:19]=3)[C:14]([OH:16])=[O:15])[CH:8]=2)[NH:3]1.[O:20]=[C:21]1[C:26]2=[CH:27][NH:28][C:29]([CH:30]=O)=[C:25]2[CH2:24][CH2:23][O:22]1>>[O:1]=[C:2]1[C:10](=[CH:30][C:29]2[NH:28][CH:27]=[C:26]3[C:21](=[O:20])[O:22][CH2:23][CH2:24][C:25]=23)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:11]3[CH:12]=[C:13]([CH:17]=[CH:18][CH:19]=3)[C:14]([OH:16])=[O:15])[CH:8]=2)[NH:3]1

Participants

3

Reactant 2

HCID 98340494-Oxo-2,4,6,7-tetrahydropyrano[3,4-C]pyrrole-1-carbaldehydeHCID 184147043-(2-Oxo-2,3-dihydro-1H-indol-5-yl)-benzoic acid

Product 1

HCID 697070873-[2-Oxo-3-(4-oxo-2,4,6,7-tetrahydro-pyrano[3,4-c]pyrrol-1-ylmethylene)-2,3-dihydro-1H-indol-5-yl]-benzoic acid

Procedure

3-(2-Oxo-2,3-dihydro-1H-indol-5-yl)-benzoic acid was condensed with 4-oxo-2,4,6,7-tetrahydro-pyrano[3,4-c]pyrrole-1-carbaldehyde to give the title compound.

Sources & evidence

ORD record
ord-c0a5d9f1748f45cd99a61d61b0985ffc
Source dataset
uspto-grants-2002_10
Patent number
US06465507B2

Reaction notes

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