Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 6-Chloro-1,3-dihydroindol-2-one | HCID 736344 | — |
| Reactant | 4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde | HCID 9964189 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 69707604 | HCID 69707604 | — |
Reaction Steps
A mixture of 6-chloro-1,3-dihydro-indol-2-one (33.5 mg, 0.2 mmol), 4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde (1 equivalent) and 0.1 mL of piperidine in ethanol (1 mL) was heated in a sealed tube at 80° C. for 3 hours. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give the title compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06465507B2 |
|---|
| Source dataset | uspto-grants-2002_10 |
|---|
| ORD ID | ord-1c5796187433461d963a2e36f5b0cf01 |
|---|
| Source note | uspto-grants-2002_10 |
|---|
