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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 991834Generated: November 1, 2026

Piperidine → HCID 69707866, compound

https://huagongshe.com/reaction/991834

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamideHCID 9816185—
Reactant4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehydeHCID 9964189—
SolventEthanolHCID 702—
ProductHCID 69707866HCID 69707866—

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of 2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamide (48 mg, 0.2 mmol), 4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde (1 equivalent) and 0.1 mL of piperidine in ethanol (1 mL) was heated in a sealed tube at 80° C. for 3 hours. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give the title compound as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06465507B2
Source datasetuspto-grants-2002_10
ORD IDord-0e1c076798c2485890589ba066e73a8e
Source noteuspto-grants-2002_10