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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 991836Generated: November 2, 2026

Piperidine → HCID 69707831, compound

https://huagongshe.com/reaction/991836

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehydeHCID 9964189—
ReactantHCID 10192651HCID 10192651—
SolventEthanolHCID 702—
ProductHCID 69707831HCID 69707831—

Reaction Conditions

Temperature80 °C

Reaction Steps

A mixture of 2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid dimethylamide (40.8 mg, 0.2 mmol), 4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde (1 eq.) and 0.1 mL of piperidine in ethanol (1 mL) was heated in a sealed tube at 80° C. for 3 hours. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give the title compound as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06465507B2
Source datasetuspto-grants-2002_10
ORD IDord-f5713dc83083492fa72974fdadf4baf9
Source noteuspto-grants-2002_10