HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 991848Generated: November 1, 2026
Piperidine → 2-Oxo-3-(4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridin-1-ylmethylene)-2,3-dihydro-1H-indole-5-sulfonic acid methylamide
https://huagongshe.com/reaction/991848
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 5-methyl-4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde | HCID 9920526 | — |
| Reactant | N-methyl-2-oxoindoline-5-sulfonamide | HCID 10176909 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Oxo-3-(4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridin-1-ylmethylene)-2,3-dihydro-1H-indole-5-sulfonic acid methylamide | HCID 69707923 | — |
Reaction Steps
A mixture of 2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid methylamide (45.2 mg, 0.2 mmol), 5-methyl-4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde (35.6 mg, 0.2 mmol) and piperidine (0.1 mL) in ethanol (1 mL) was heated at 80° C. for 4 hours. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06465507B2 |
|---|
| Source dataset | uspto-grants-2002_10 |
|---|
| ORD ID | ord-32b52e8950ab49a89e6f2094cfbb39bf |
|---|
| Source note | uspto-grants-2002_10 |
|---|