HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 991849Generated: October 29, 2026
Piperidine → 2-Oxo-3-(4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridin-1-ylmethylene)-2,3-dihydro-1H-indole-5-sulfonic acid methylamide
https://huagongshe.com/reaction/991849
Participants
| Role | Name | HCID | Charge |
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| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamide | HCID 9816185 | — |
| Reactant | 5-methyl-4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde | HCID 9920526 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Oxo-3-(4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridin-1-ylmethylene)-2,3-dihydro-1H-indole-5-sulfonic acid methylamide | HCID 69707923 | — |
Reaction Steps
A mixture of 2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid dimethylamide (48 mg, 0.2 mmol), 5-methyl-4-oxo-4,5,6,7-tetrahydro-2H-pyrrolo[3,4-c]pyridine-1-carbaldehyde (35.6 mg, 0.2 mmol) and piperidine (0.1 mL) in ethanol (1 mL) was heated at 80° C. for 4 hours. The precipitate was collected by vacuum filtration, washed with ethanol and dried to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06465507B2 |
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| Source dataset | uspto-grants-2002_10 |
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| ORD ID | ord-3bb85b931c3343c6b06bfb47b655d9fb |
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| Source note | uspto-grants-2002_10 |
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