Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Toluenesulfonic acid → Acrylamidomethyl 2-oxopyrrolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Toluenesulfonic acid | HCID 6101 | — |
| 반응물 | Acrylamide | HCID 6579 | — |
| 반응물 | Phenothiazine | HCID 7108 | — |
| 반응물 | 1-(Methoxymethyl)-2-pyrrolidinone | HCID 13624830 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Acrylamidomethyl 2-oxopyrrolidine | HCID 18414899 | 40% |
반응 단계
A mixture of 65.6 g of 1-methoxymethyl-2-pyrrolidone, 75.5 g of acrylarnide, 0.20 g of p-toluene sulfonic acid and 0.20 g of phenothiazine was stirred under N2 atmosphere at 150° C. for 1 hour, during which time the methanol was removed by distillation. The residue was cooled, and recrystallized from acetone to give the title compound in a yield of 40%. mp: 73-74° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06465588B1 |
| 출처 데이터셋 | uspto-grants-2002_10 |
| ORD ID | ord-2c4bf1dc13d9444a977d82b3489b7370 |
| 출처 메모 | uspto-grants-2002_10 |