HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromophenol → 4-Bromophenyl phosphorodichloridate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromophenol | HCID 7808 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Product | 4-Bromophenyl phosphorodichloridate | HCID 21864551 | — |
Reaction Steps
Phosphorous oxychloride is reacted with a para-bromophenol moiety to form para-bromophenyl phosphorodichloridate. Without purification, the para-bromophenyl phosphorodichloridate is contacted with alanine methyl ester to produce para-bromophenyl methoxyalaninyl phosphorochloridate. Without purification, the para-bromophenyl methoxyalaninyl phosphorochloridate is reacted with AZT.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465641B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-9fcd662047fe45f7b7d9868ad265af88 |
| Source note | uspto-grants-2002_10 |