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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 991911Generated: November 3, 2026

Acetaldehyde → alpha-Methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline-2-methanol

https://huagongshe.com/reaction/991911

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetaldehydeHCID 177—
ReactantDeaminoimiquimodHCID 11424651—
Productalpha-Methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline-2-methanolHCID 15224403—

Reaction Steps

Using the general method of Example 45, 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline (20 g; 89 mmol) was reacted with acetaldehyde to provide the desired product. The structure was confirmed by nuclear magnetic resonance spectroscopy.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06465654B2
Source datasetuspto-grants-2002_10
ORD IDord-83febce531184ae9ab086bf8d81bd940
Source noteuspto-grants-2002_10