HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminoadamantane → HCID 18414554, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminoadamantane | HCID 25332 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | (Dimethyl sulfide)trihydroboron | HCID 12423031 | — |
| Reactant | HCID 54201341 | HCID 54201341 | — |
| Reactant | HCID 131722572 | HCID 131722572 | — |
| Product | HCID 18414554 | HCID 18414554 | 98% |
Reaction Steps
Prepared as in Example 112, using 2-aminoadamantane for the coupling with 2-(2, 5-dimethylpyrrolyl)-6-(4-(carboxymethyl)phenyl)-pyridine followed by deblocking with hydroxylamine hydrochloride and borane methyl sulfide reduction in 98% yield, mp 215-230° C. (dec.) as the hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465491B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-ed6716353c754e609f1895a98f2286b8 |
| Source note | uspto-grants-2002_10 |