HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxycyclohex-2-en-1-one → 3-Butylcyclohex-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxycyclohex-2-en-1-one | HCID 85597 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 3-Butylcyclohex-2-en-1-one | HCID 239095 | 97.2% |
Reaction Steps
The general procedure for the preparation of substrates using 3-methoxycyclohexenone (1.26 g, 10 mmol) and n-BuLi (20 mmol, 1.6 M in hexane) gave, after flash chromatography (4:1 hexanes:ethyl acetate) the title compound as a colorless liquid (1.48 g, 97%). Spectroscopic data were consistent with previously reported data for this compound.2
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465664B1 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-f6b9a0c106964458a1305af9c5ac6163 |
| Source note | uspto-grants-2002_10 |