HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloroindole → 3-(1,4-Dioxa-spiro[4,5]dec-7-en-8-yl)-5-chloro-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloroindole | HCID 87110 | — |
| Reactant | 3-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-1H-indole | HCID 2763857 | — |
| Product | 3-(1,4-Dioxa-spiro[4,5]dec-7-en-8-yl)-5-chloro-1H-indole | HCID 18414154 | 96% |
Reaction Steps
This compound was prepared in the manner described above for intermediate 1a by replacing indole with 5-chloroindole (5 g, 33 mmol)) to afford 9.14 g (96%) of the title compound as a white solid: mp 178-181° C.; MS EI m/e 273 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465482B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-c6e7407ba8d9416e907bc501ce62a418 |
| Source note | uspto-grants-2002_10 |