HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole-5-carbonitrile → 3-(1,4-Dioxaspiro[4.5]dec-7-EN-8-YL)-1H-indole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole-5-carbonitrile | HCID 27513 | — |
| Reactant | 3-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-1H-indole | HCID 2763857 | — |
| Product | 3-(1,4-Dioxaspiro[4.5]dec-7-EN-8-YL)-1H-indole-5-carbonitrile | HCID 15521972 | 50% |
Reaction Steps
This compound was prepared in the manner described above for intermediate 1a by replacing indole with 5-cyanoindole (29.98 g, 0.21 mol) to afford 29.32 g (50%) of the title compound as a white solid: mp 158-160° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465482B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-d3159fef6c454fbdb1f705f741fc5869 |
| Source note | uspto-grants-2002_10 |