HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole → 3-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-5-methoxy-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole | HCID 798 | — |
| Reactant | 3-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-1H-indole | HCID 2763857 | — |
| Reactant | 2-methoxy-1H-indole | HCID 17763644 | — |
| Product | 3-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-5-methoxy-1H-indole | HCID 2764086 | 82% |
Reaction Steps
This compound was prepared in the manner described above for intermediate 1a by replacing indole with 5 methoxy indole (5 g, 34 mmol) in 82% yield (7.95 g) as a white solid: mp 161-162° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465482B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-493b61a5bc214fe9a0ed301eb13754a7 |
| Source note | uspto-grants-2002_10 |