Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(1H-Indol-3-YL)cyclohexanone → 3-(4-oxocyclohexyl)-1H-indole-5-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(1H-Indol-3-YL)cyclohexanone | HCID 10846264 | — |
| 반응물 | 3-(1,4-Dioxa-spiro[4,5]dec-8-yl)-5-cyano-1H-indole | HCID 15521973 | — |
| 생성물 | 3-(4-oxocyclohexyl)-1H-indole-5-carbonitrile | HCID 11241886 | 81% |
반응 단계
This compound was prepared in the manner described above for intermediate 3a by replacing 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-1H-indole with 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-5-cyano-1H-indole (6 g) to afford 4.03 g (81%) of the title compound as a white solid: mp 162.5-164° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06465482B2 |
| 출처 데이터셋 | uspto-grants-2002_10 |
| ORD ID | ord-e837f87c58924bffbedfc5c83d9c49fd |
| 출처 메모 | uspto-grants-2002_10 |