HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(1,4-Dioxa-spiro[4,5]dec-8-yl)-5-methoxy-1H-indole → 4-(5-Methoxy-1H-indol-3-YL)cyclohexanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(1,4-Dioxa-spiro[4,5]dec-8-yl)-5-methoxy-1H-indole | HCID 10589372 | — |
| Reactant | 4-(1H-Indol-3-YL)cyclohexanone | HCID 10846264 | — |
| Product | 4-(5-Methoxy-1H-indol-3-YL)cyclohexanone | HCID 10538200 | 85% |
Reaction Steps
This compound was prepared in the manner described above for intermediate 3a by replacing 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-1H-indole with 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-5-methoxy-1H-indole (5.85 g) to afford 4.2 g (85%) of the title compound as a white solid: mp 103-106° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465482B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-8e08e96d9495422da19cd2777fe19e0c |
| Source note | uspto-grants-2002_10 |