HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1H-Indol-3-YL)cyclohexanone → 4-(2-Methyl-1H-3-indolyl)-cyclohexanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1H-Indol-3-YL)cyclohexanone | HCID 10846264 | — |
| Reactant | 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-2-methyl-1H-indole | HCID 18414099 | — |
| Product | 4-(2-Methyl-1H-3-indolyl)-cyclohexanone | HCID 18414056 | 88% |
Reaction Steps
This compound was prepared in the manner described above for intermediate 3a by replacing 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-1H-indole with 3-(1,4-dioxa-spiro[4,5]dec-8-yl)-2-methyl-1H-indole (2.2 g) to afford 1.62 g (88%) of the title compound as a yellow thick oil: MS EI m/e 227 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06465482B2 |
| Source dataset | uspto-grants-2002_10 |
| ORD ID | ord-1bf012105adc44659df435f4a1aacab0 |
| Source note | uspto-grants-2002_10 |