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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 992055Generated: November 1, 2026

HCID 18414093, compound → 4-(6-Methoxy-3-methylquinolin-8-yl)piperazine

https://huagongshe.com/reaction/992055

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 18414093HCID 18414093—
ReactantHCID 18414117HCID 18414117—
Reactant4-(6-Methoxy-2-methylquinolin-8-yl)piperazineHCID 18414150—
Product4-(6-Methoxy-3-methylquinolin-8-yl)piperazineHCID 18414057—

Reaction Steps

The title compound was prepared by the same method used for the preparation of 4-(6-methoxy-2-methylquinolin-8-yl)piperazine, except 1-benzyl-4-(6-methoxy-3-methylquinolin-8-yl)piperazine (0.32 g, 0.92 mmol) was substituted for the 1-benzyl-4-(6-methoxy-2-methylquinolin-8-yl)piperazine. The title compound was isolated in nearly quantitative yield and used with purification in the subsequent reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06465482B2
Source datasetuspto-grants-2002_10
ORD IDord-3f51485d72364c59863e3f44b42feb32
Source noteuspto-grants-2002_10