Cholesterol → HCID 57070769, compound

Participants

Reaction Steps

A solution of 6 ml of methacryloyl chloride in 30 ml of dichloromethane is added dropwise to 20 g (51.72 mmol) of cholesterol and 8 ml of triethylamine in 170 ml of dichloromethane (abs.). The mixture is stirred overnight at room temperature. The solvent is distilled off under reduced pressure, and the residue is recrystallized three times from the ca. 400 ml of ethanol (95%). Drying is carried out at a pressure of 10−2 mbar for 24 h

Provenance & Evidence