HCID 18411544, compound → HCID 18411532, compound

HRID 992205Notes

Reaction equation

HRID 992205 reaction equation
[CH3:1][C:2]1[N:3]=[N:4][S:5][C:6]=1[C:7]1[S:8][CH:9]=[C:10]([CH2:12][OH:13])[N:11]=1>C(Cl)Cl.CO.O=[Mn]=O>[CH3:1][C:2]1[N:3]=[N:4][S:5][C:6]=1[C:7]1[S:8][CH:9]=[C:10]([CH:12]=[O:13])[N:11]=1

Participants

5

Reactant 1

HCID 18411544HCID 18411544, compound

Product 1

HCID 18411532HCID 18411532, compound

Reagents, catalysts & solvents 3

HCID 14801Manganese dioxideCatalystHCID 887MethanolSolventHCID 6344DichloromethaneSolvent

Procedure

A mixture of [2-(4-methyl[1,2,3]thiadiazol-5-yl)thiazol-4-yl]methanol (1.06 g; 4.97 mmol) and MnO2 (8.64 g; 99.39 mmol) in CH2Cl2 (100 ml) and methanol (10 ml) was refluxed for 6 hours.

Workup

  1. temperaturewas refluxed for 6 hours

Sources & evidence

ORD record
ord-fee8f8f1e0da4ca4995cd166a9f0b4f6
Source dataset
uspto-grants-2002_10
Patent number
US06468979B1

Reaction notes

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