HCID 18411547, compound → 2-(1H-Imidazol-1-yl)-4-thiazolecarboxaldehyde
Reaction equation
[N:1]1([C:6]2[S:7][CH:8]=[C:9]([CH2:11][OH:12])[N:10]=2)[CH:5]=[CH:4][N:3]=[CH:2]1>C(Cl)Cl.O=[Mn]=O>[N:1]1([C:6]2[S:7][CH:8]=[C:9]([CH:11]=[O:12])[N:10]=2)[CH:5]=[CH:4][N:3]=[CH:2]1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
MnO2 (3.28 g; 37.75 mmol) was added to a solution of (2-imidazol-1-ylthiazol-4-yl)methanol (0.33 g; 1.82 mmol), prepared as described in the above step, in CH2Cl2 (30 ml).
Workup
- customprepared
Sources & evidence
- ORD record
- ord-9d7c80a4ac4f42228dfa34b0fecd3dc8
- Source dataset
- uspto-grants-2002_10
- Patent number
- US06468979B1
Reaction notes
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