HCID 18411546, compound → HCID 18411540, compound

HRID 992212Notes

Reaction equation

HRID 992212 reaction equation
[OH:1][CH2:2][C:3]1[N:4]=[C:5]([N:8]2[CH2:12][CH2:11][O:10][C:9]2=[O:13])[S:6][CH:7]=1>C(Cl)(Cl)Cl.CO.O=[Mn]=O>[O:13]=[C:9]1[N:8]([C:5]2[S:6][CH:7]=[C:3]([CH:2]=[O:1])[N:4]=2)[CH2:12][CH2:11][O:10]1

Participants

5

Reactant 1

HCID 18411546HCID 18411546, compound

Product 1

HCID 18411540HCID 18411540, compound

Reagents, catalysts & solvents 3

HCID 14801Manganese dioxideCatalystHCID 887MethanolSolventHCID 6212ChloroformSolvent

Procedure

MnO2 (7.2 g; 83.6 mmol) was added to a solution of 3-(4-hydroxymethylthiazole-2-yl)oxazolidin-2-one (0.56 g; 2.8 mmol), prepared as described in the above step, in chloroform (60 ml) and methanol (6 ml).

Workup

  1. customprepared

Sources & evidence

ORD record
ord-8dbe6656a68346b3a9392ba55afc9bd9
Source dataset
uspto-grants-2002_10
Patent number
US06468979B1

Reaction notes

Loading…