huagongshe.com
HRID992229

反应详情

EQUATION

反应方程式

HRID 992229 的结构方程式

REACTANTS

反应物

2
结构：NCC(=O)O
HCID750

Glycine

C2H5NO2

结构：O=C1OC(=O)c2cc([N+](=O)[O-])ccc21
HCID230976

4-Nitrophthalic anhydride

C8H3NO5

PRODUCTS

生成物

1
结构：O=C(O)CN1C(=O)c2ccc([N+](=O)[O-])cc2C1=O
HCID272737

(5-Nitro-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid

C10H6N2O6

收率 86.1%

PROCEDURE

实验过程

4-nitrophthalic anhydride (0.25 g, 0.0013 mol) and glycine (0.097 g, 0.0013 mol) were refluxed as above overnight. The clear solution was purified as per 120 to yield 0.28 g (86%) 140 as very pale yellow crystals: mp=195-96° C.; Rf0.79 (A): Rf0.75 (B): Rf0.28 (D): IR (cm−1): 2811-3150 (OH), 3115 (C═CH), 1787 (C═O), 1730 (bs, C═O), 1622 (C═C), 1551 (N═O), 1412 (C═C), 1391 (C—O), 1351 (N═O), 1117 (C—O), 720 (C═CH); MS m/z (rel intensity) 250 (7), 249 (62), 205 (100), 122 (10).

WORKUP

后处理

  1. customThe clear solution was purified as per 120